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Hilde Nilsen Selected Research

Uracil-DNA Glycosidase

3/2021Erratum: The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID.
9/2020The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID.
2/2010Caenorhabditis elegans APN-1 plays a vital role in maintaining genome stability.
12/2005Monoclonal B-cell hyperplasia and leukocyte imbalance precede development of B-cell malignancies in uracil-DNA glycosylase deficient mice.
4/2005Mutation frequencies and AID activation state in B-cell lymphomas from Ung-deficient mice.
8/2003Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas.

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Hilde Nilsen Research Topics

Disease

13Neoplasms (Cancer)
07/2022 - 08/2003
4Mitochondrial Diseases (Mitochondrial Disease)
01/2018 - 05/2014
3Parkinson Disease (Parkinson's Disease)
01/2022 - 01/2019
3Genomic Instability
01/2021 - 02/2011
3Fatigue
01/2020 - 11/2017
2Ataxia Telangiectasia (Louis Bar Syndrome)
01/2020 - 05/2014
2Alzheimer Disease (Alzheimer's Disease)
01/2020 - 01/2019
2Cockayne Syndrome (Syndrome, Cockayne)
11/2016 - 05/2014
2Cadaver (Cadavers)
08/2010 - 02/2010
2B-Cell Lymphoma (Lymphoma, B Cell)
04/2005 - 08/2003
1Atherosclerosis
01/2021
1Atherosclerotic Plaque (Atheroma)
01/2021
1Genetic Translocation (Chromosomal Translocation)
09/2020
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2020
1Sepsis (Septicemia)
01/2020
1Premature Aging
11/2019
1Werner Syndrome (Werner's Syndrome)
11/2019
1Chronic Fatigue Syndrome (Myalgic Encephalomyelitis)
01/2019
1DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes)
01/2018
1Thyroid Neoplasms (Thyroid Cancer)
01/2018
1Atrophy
11/2017
1Inflammation (Inflammations)
11/2017
1Common Variable Immunodeficiency
01/2017
1Neuroblastoma
11/2016
1Friedreich Ataxia (Friedreich's Ataxia)
10/2016
1Cardiomyopathies (Cardiomyopathy)
10/2016
1Xeroderma Pigmentosum (Kaposi's Disease)
05/2014
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2012
1Hyperplasia
12/2005

Drug/Important Bio-Agent (IBA)

6Uracil-DNA GlycosidaseIBA
03/2021 - 08/2003
6DNA (Deoxyribonucleic Acid)IBA
01/2018 - 01/2008
5EnzymesIBA
10/2019 - 01/2008
4DNA Glycosylases (DNA Glycosylase)IBA
01/2021 - 01/2008
3NAD (NADH)IBA
01/2020 - 10/2016
3A-Form DNA (A-DNA)IBA
11/2016 - 08/2003
2Biomarkers (Surrogate Marker)IBA
01/2022 - 11/2017
2UracilIBA
10/2019 - 02/2010
2NucleotidesIBA
01/2018 - 05/2014
2ParaquatIBA
01/2018 - 08/2010
2Proteins (Proteins, Gene)FDA Link
11/2016 - 01/2008
1SynucleinsIBA
01/2022
1RNA (Ribonucleic Acid)IBA
01/2021
1Apolipoproteins E (ApoE)IBA
01/2021
1LipidsIBA
01/2021
1Messenger RNA (mRNA)IBA
01/2021
1AICDA (activation-induced cytidine deaminase)IBA
09/2020
1nicotinamide-beta-ribosideIBA
01/2020
1DNA HelicasesIBA
11/2019
1Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2019
1actinoninIBA
01/2019
1Amyloid (Amyloid Fibrils)IBA
01/2019
13,8-dihydroxy-6H-dibenzo(b,d)pyran-6-oneIBA
01/2019
1Mitochondrial DNA (mtDNA)IBA
01/2018
1Small Interfering RNA (siRNA)IBA
01/2018
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2018
1tomatidineIBA
11/2017
1Antiviral Agents (Antivirals)IBA
11/2017
1LigandsIBA
01/2017
1OligodeoxyribonucleotidesIBA
01/2017
1CPG-oligonucleotideIBA
01/2017
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
11/2016
1B-Form DNA (B-DNA)IBA
11/2016
1Ribosomal DNA (rDNA)IBA
11/2016
1Interferon-gamma (Interferon, gamma)IBA
10/2016
1EndonucleasesIBA
01/2013
1Fluorouracil (Carac)FDA LinkGeneric
01/2013
1Therapeutic UsesIBA
01/2012
1Valproic Acid (Depakote)FDA LinkGeneric
01/2012
1Histones (Histone)IBA
01/2012
1Histone Deacetylase InhibitorsIBA
01/2012
1DNA Repair EnzymesIBA
01/2008
1dUTP pyrophosphataseIBA
01/2008

Therapy/Procedure

2Precision Medicine
07/2022 - 01/2022
2Therapeutics
01/2022 - 01/2012